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Reflecting on Yom Kippur Through the Lens of Genetics

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By Becca Bakal 

Much of the liturgy around Yom Kippur centers on the unknowns in our lives. In particular, the poem Unetanah Tokef, which we read on Rosh Hashanah and Yom Kippur, focuses on the mysteries of the future. The poem describes how each person’s fate is written and sealed during the High Holidays, including who will live, who will die, and how they will pass on. The text also lists various blessings and challenges that may be part of someone’s life.  

This metaphor of fate being “inscribed” in the Book of Life or the Book of Death is similar to how people often talk about their genetics. On more than one occasion, I’ve had a friend with a strong family history of cancer say, “Well, I guess I’m doomed.”  

The poem’s descriptions of life and death seem to confirm that many of us will meet an unhappy end, even if we don’t know it yet:  

How many shall pass away and how many shall be born,  
Who shall die in old age, and who before their time, 
Who shall live and who shall die, 
Who shall perish by water and who by fire, 
Who by sword and who by wild beast, 
Who by famine and who by thirst, 
Who by earthquake and who by plague, 
Who by strangulation and who by stoning, 

The poem paints a picture of various characters in a book—they may not yet know what will happen to them, but their story is unfolding along a predetermined path.   

While our liturgy emphasizes that aspects of our lives are out of our control, that’s not the only message. Unetaneh Tokef also tells us that we have the opportunity—and responsibility—to take ownership over our lives through our actions. After the laundry list of blessings and curses, the poem continues: 

But repentance, prayer, and righteousness annul the severe decree. 

According to this tradition, we do have an opportunity to alter the course of our lives. That’s true, too, when it comes to genetics. Our genetics may increase our chances of a specific disease, but DNA is not fate.   

In particular, there are various ways that you can reduce your genetic risks. Take the opportunity of these High Holy Days to protect your family’s health. Here are a few steps you can take: 

  • If you’re planning to start a family or you know someone who is, then seek out carrier screening. Screening before pregnancy gives couples the most options 

  • To address your risk of cancer: 

The Sarnoff Center wishes you a sweet New Year, and an easy fast.  


Affordable, Accessible Genetic Screening in Illinois

Our affordable, accessible carrier screening program uses advanced technology to provide comprehensive screening for Jewish and interfaith couples. Visit our Get Screened page to learn more and register.


Planning for a Family?

1 in 4 Jews carries a potentially devastating genetic disorder that could pass down to a child. Make carrier screening part of your family planning process. 


Do You Know What's In Your Genes?

What is the most valuable gift you can give to your family? The gift of good health! There are many health conditions that run in families. Knowing your family health history can alert you to the potential risk for a variety of genetic disorders . Talk to your relatives for warning signs and assess your risk for hereditary cancers.

Did you know: Ashkenazi Jews are 10 TIMES more likely to have BRCA mutations, which significantly increases lifetime risks for hereditary cancers, so what does this heightened risk mean for you? Click here to learn more .